The skin on the neck presents unique challenges. It is approximately 40% thinner than facial skin, contains fewer sebaceous glands, and is subjected to constant mechanical stress from flexion and extension. These factors, combined with cumulative UV exposure, accelerate the visible signs of aging—horizontal lines or creases that go across your neck like little rings (necklace lines), loss of elasticity, platysmal banding (the two vertical muscle cords that pop out in the front of your neck), and poikiloderma (mottled, blotchy look on the neck) —often years ahead of the face.

Emerging clinical evidence identifies Proxylane (hydroxypropyl tetrahydropyranotriol) and N-Acetyl Glucosamine (NAG) as a particularly effective synergistic pair for structural neck rejuvenation. Proxylane significantly upregulates glycosaminoglycan (GAG) synthesis and increases dermal thickness. NAG, a physiological precursor of hyaluronic acid, amplifies endogenous HA production, providing both immediate hydration and sustained volumetric restoration.

Used together twice daily in a dedicated neck formulation, this duo triggers a powerful feedback loop through CD44 receptor upregulation, yielding smoother topography, restored cervical contour, and a firmer, more resilient texture.

The message is clear: treating the neck as an afterthought is outdated. With the evidence-based power of Proxylane and N-Acetylglucosamine, we can finally give ourselves a neck that no longer betrays our age.